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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Metabolism. 2013 Aug 28;62(12):10.1016/j.metabol.2013.07.010. doi: 10.1016/j.metabol.2013.07.010

Figure 1.

Figure 1

Increased adiponectin improves systemic metabolism under conditions of long-term diet-induced obesity. a) Insulin tolerance test was performed on mice after overnight fasting. b) mRNA expression levels of Glut4 were determined in epididymal fat pads from mice in each group and are expressed as relative to wild type with upper and lower confidence intervals represented. c) Endpoint serum levels of insulin, d) leptin, and e) free fatty acids were assessed using commercially available assays. f) Sections from apn-deficient (apn-KO), wild type, and adiponectin over-expressing (apn-TG) liver were stained with oil red O. Data are shown as means ± SEM and represent apn-KO (n=9); wild type (n=11); apn-TG (n=8) *P<0.05, vs. apn-KO and wild type; †P<0.001, vs. apn-KO and wild type.