. Author manuscript; available in PMC: 2014 Dec 1.

Published in final edited form as: Am J Ophthalmol. 2013 Sep 25;156(6):10.1016/j.ajo.2013.08.001. doi: 10.1016/j.ajo.2013.08.001

Table 4.

Frequency of statistically abnormal measurements as flagged on the retinal nerve fiber layer and Ganglion Cell Analysis printouts of Cirrus high-definition optical coherence tomography in the normal control subjects and glaucoma patients.

OCT parameters	Normal group		Glaucoma group		Positive Likelihood Ratio		Negative Likelihood Ratio
OCT parameters	p<5%	p<1%	p<5%	p<1%	p<5%	p<1%	p<5% considered abnormal	Only p<1% considered abnormal
Average RNFL	10 (11%)	8 (8.8%)	42 (71.2%)	25 (42.4%)	6.47 (3.53-11.88)	4.82 (2.33-9.96)	0.32 (0.22-0.49)	0.63 (0.50-0.79)
Average GC/IPL	10 (11%)	5 (5.5%)	37 (62.7%)	30 (50.9%)	5.71 (3.08-10.6)	9.25 (3.81-22.50)	0.42 (0.30-0.59)	0.52 (0.40-0.68)
RNFL quadrant	11(12.1%)	9 (9.9%)	55 (93.2%)	49 (83.1%)	7.71 (4.41-13.49)	8.39 (4.47-15.78)	0.08 (0.03-0.20)	0.18 (0.11-0.33)
RNFL sectors	27(29.7%)	4 (4.4%)	57 (96.6%)	49 (83.1%)	3.25 (2.37-4.48)	18.89 (7.2-49.60)	0.05 (0.01-0.19)	0.18 (0.10-0.31)
GC/IPL sectors	8 (8.8%)	6 (6.6%)	53 (89.8%)	49 (83.1%)	10.22 (5.24-19.92)	12.60 (5.76-27.53)	0.11 (0.05-0.24)	0.18 (0.10-0.32)
Min GC/IPL	7 (7.7%)	6 (6.6%)	50 (84.8%)	42 (71.2%)	11.02 (5.36-22.63)	10.80 (4.90-23.79)	0.16 (0.09-0.30)	0.30 (0.21-0.46)

OCT: Optical Coherence Tomography; RNFL: Retinal Nerve Fiber Layer; GC/IPL: Ganglion Cell/inner plexiform layer; Min: Minimum.