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. 2013 Nov 19;8(11):e81095. doi: 10.1371/journal.pone.0081095

Figure 2. Tissue destruction of ileum by M90T infection followed by rapid recovery.

Figure 2

(A) Hematoxylin-eosin (H&E) staining of terminal ileum following oral M90T or M90T∆IpaB4 infection. Epithelial shedding (*), tissue regeneration (arrowhead). (B) Confocal image of E-cadherin (green) for epithelium structure and DAPI (blue) staining for nucleus from terminal ileum. (C) Pathological score assessment from terminal ileum H&E histology following oral M90T infection by a blind test. (n >20). Not significant (ns), ***< P=0.0001. (D-E) Scanning electron microscopy (SEM) images of dome region of PP (D) and intestinal villi (E) in terminal ileum following oral M90T infection. Lumen (Lu), epithelial cells (EC), lamina propria (LP) (n=10).