Table 2. Relationships of FGF19 and FGF21 with clinical, anthropometric and biochemical parameters calculated in a combined population of healthy pregnant controls and patients with GDM (n = 90).
Serum FGF19 | Serum FGF21 | |||
r | P | r | P | |
Age (years) | −0.072 | 0.498 | 0.011 | 0.921 |
Gestational age at OGTT (weeks) | −0.056 | 0.599 | −0.007 | 0.945 |
Body mass index before pregnancy (kg/m2) | −0.157 | 0.138 | 0.206 | 0.052 |
Systolic blood pressure (mm Hg) | −0.165 | 0.120 | 0.192 | 0.070 |
Diastolic blood pressure (mm Hg) | −0.021 | 0.844 | 0.158 | 0.138 |
Glucose 0 h (mmol/L) | −0.383 | <0.001* | 0.274 | 0.009* |
Glucose 1 h (mmol/L) | −0.242 | 0.022* | 0.190 | 0.073 |
Glucose 2 h (mmol/L) | −0.201 | 0.054 | 0.184 | 0.082 |
Fasting insulin (µU/ml) | −0.351 | <0.001* | 0.259 | 0.014* |
HOMA-IR | −0.413 | <0.001* | 0.289 | 0.006* |
Creatinine (µmol/L) | 0.041 | 0.661 | 0.132 | 0.144 |
Triglycerides (mmol/L) | −0.227 | 0.031* | 0.395 | <0.001* |
Total cholesterol (mmol/L) | 0.095 | 0.373 | −0.108 | 0.313 |
HDL cholesterol (mmol/L) | 0.096 | 0.367 | −0.063 | 0.555 |
LDL cholesterol (mmol/L) | 0.050 | 0.642 | −0.010 | 0.926 |
Adiponectin (µg/ml) | 0.431 | <0.001* | −0.377 | <0.001* |
The correlations were calculated in the combined population of GDM patients and controls. Units and abbreviations are as Table 1.
*Significant correlation as assessed by Spearman correlation method.