Table IV.
Cox regression was generated to compare TTP and OS between responders and non-responders according to the four response criteria.
| TTP | OS | ||||
|---|---|---|---|---|---|
|
|
|
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| Response criteria | n | HR (95% CI) | P-value | HR (95% CI) | P-value |
| RECIST | |||||
| Responders | 25 | 0.74 (0.43–1.27) | 0.274 | 0.99 (0.58–1.70) | 0.965 |
| Non-responders | 88 | 1.0 | 1.0 | ||
| mRECIST | |||||
| Responders | 29 | 0.42 (0.24–0.74) | 0.003 | 0.61 (0.35–1.06) | 0.080 |
| Non-responders | 84 | 1.0 | 1.0 | ||
| Choi | |||||
| Responders | 88 | 0.46 (0.28–0.77) | 0.003 | 0.47 (0.28–0.78) | 0.004 |
| Non-responders | 25 | 1.0 | 1.0 | ||
| Modified Choi | |||||
| Responders | 40 | 0.64 (0.40–1.05) | 0.075 | 0.64 (0.39–1.04) | 0.072 |
| Non-responders | 73 | 1.0 | 1.0 | ||
RECIST, Response Evaluation Criteria in Solid Tumors; mRECIST, modified Response Evaluation Criteria in Solid Tumors; TTP, time to progression; OS, overall survival; HR, hazard ratio; CI, confidence interval.