Table 1.

The inhibitory concentration of SERMs in MCF-7 and TAM-R cells

SERMs	IC50		P value summary
	MCF-7	TAM-R
TAM	20.5 ± 4.0	27.0 ± 1.9	*
4-OH TAM	11.3 ± 0.6	18.3 ± 1.1	***
TOR	18.9 ± 4.1	13.7 ± 1.2	ns
OSP	12.6 ± 0.3	12.7 ± 0.3	ns
IDO	6.5 ± 0.6	9.6 ± 0.5	***
RAL	13.7 ± 0.3	15.7 ± 0.7	**

Data are expressed as mean ± S.D. of three independent experiments. ns stands for not significance.

^*, ^**, ^*** p< 0.05, 0.01, and 0.001 in comparison with MCF-7, respectively.