Table 2.

Changes in paw thicknesses of the mice

Group	Paw thicknesses		Differences [% changes*]
	At start of treatment	At sacrifice
Controls
Vehicle	2.45 ± 0.15	2.51 ± 0.07	0.05 ± 0.19
Formalin	2.46 ± 0.16	4.21 ± 0.26a	1.75 ± 0.41a
Dexamethasone	2.47 ± 0.12	2.67 ± 0.20b	0.21 ± 0.20b [−88.27]
DHU001 treatment
500 mg/kg	2.45 ± 0.11	3.26 ± 0.28ab	0.81 ± 0.31ab [−53.75]
250 mg/kg	2.45 ± 0.19	3.45 ± 0.35ab	1.00 ± 0.43ab [−42.99]
125 mg/kg	2.45 ± 0.13	3.78 ± 0.17ab	1.33 ± 0.19ac [−23.82]

Values are expressed as Mean ± SD of eight mice, mm.

Differences = paw thicknesses at sacrifice − paw thicknesses at sacrifice at start of treatment.

^* % changes between formalin control and treated group.

^ap < 0.01 as compared with vehicle control.

^bp <0.01 and ^cp < 0.05 as compared with formalin control.