Table 2.
PC50 and logRTA values for STTA assay (persistent organic pollutants)
| Test chemicals | STTA assay | |
|---|---|---|
| PC50(M) | logRTA* | |
| 17β-estradiol | 2.88 × 10−11 | 2 |
| 17α-estradiol | 3.0 × 10−9 | −0.01773 |
| Dichloro diphenyl trichloroethane (DDT) | 1.67 × 10−6 | −2.76447 |
| Dichloro diphenyl dichloro ethylene (DDE) | Negative | Negative |
| Dieldrin | Negative | Negative |
| Heptachlor | Negative | Negative |
| Aldrin | Negative | Negative |
| Chlordane | Negative | Negative |
| Lindane | Negative | Negative |
| Polybrominated diphenyl ethers (PBDE) | Negative | Negative |
*Relative transcriptional activation is calculated as 100 × (PC50) of E2/(PC50) of test compound; a value of 100 indicates that the compound tested is a full agonist.
Abbreviations: RTA, Relative transcriptional activation; PC50, the concentration of chemical estimated to cause 50% of activity of the positive control response on a plate by plate basis.