Table 4.
Comparison of in vitro assay for dichloro diphenyl trichloroethane (DDT)
Test chemicals | Yeast assay | E-screen assay | STTA assay |
---|---|---|---|
Coldhama logRP | Sotob logRPP | This study logRTA | |
17β- estradiol | 2 | 2 | 2 |
Dichloro diphenyl trichloroethane (DDT) | −4.52 | −4 | −2.76 |
a: data from Coldham et al. (1997), b: data from Soto et al. (1995).
Abbreviations: E2, 17β-estradiol; RP, relative potency compared to E2 (100) by molar mass determined with the recombinant yeast bioassay; RPP, relative proliferative potency is the ratio between 17β-estradiol and xenoestrogen doses needed to produce maximal cell yields ×100; RTA, Relative transcriptional activation.