Table 1.
Group | Intervals | ||
---|---|---|---|
Day 0a~Day 7 | Day 7~Day 13 | Day 0~Day 14b | |
Male | |||
Vehicle control | 8.84 ± 1.24 | 1.20 ± 0.38 | 7.44 ± 1.86 |
2000 mg/kg | 8.02 ± 1.39 | 1.46 ± 0.98 | 6.30 ± 2.33 |
1000 mg/kg | 7.68 ± 0.82 | 2.72 ± 0.83* | 8.08 ± 1.44 |
500 mg/kg | 8.68 ± 0.44 | 1.96 ± 1.64 | 7.68 ± 1.85 |
250 mg/kg | 7.24 ± 4.26 | 2.86 ± 5.30 | 7.54 ± 1.24 |
125 mg/kg | 8.74 ± 0.88 | 1.94 ± 0.48 | 8.02 ± 1.07 |
Female | |||
Vehicle control | 5.92 ± 2.02 | 1.56 ± 1.58 | 5.50 ± 2.23 |
2000 mg/kg | 5.46 ± 2.74 | 1.12 ± 1.78 | 4.92 ± 2.94 |
1000 mg/kg | 6.54 ± 0.79 | 1.86 ± 0.90 | 6.18 ± 1.13 |
500 mg/kg | 5.10 ± 1.80 | 1.44 ± 1.73 | 4.62 ± 2.87 |
250 mg/kg | 4.42 ± 1.18 | 2.10 ± 1.63 | 4.50 ± 1.32 |
125 mg/kg | 4.72 ± 0.83 | 3.22 ± 1.11 | 5.78 ± 0.83 |
Values are expressed as mean ± SD of five mice, g.
aDay of treatment after overnight fasted.
bDay of sacrifice after overnight fasted.
*p < 0.05 compared with male vehicle control.