Table 5.
Biochemical serum values of male rats treated orally with. G. bimaculatus over a 13-week period
| Item | Unit | CONa | 0.04 | 0.2 | 1 | 5 |
|---|---|---|---|---|---|---|
| Toal protein | g/dl | 7.0 ± 0.1 | 6.9 ± 0.3 | 7.05 ± 0.2 | 7.2 ± 0.3 | 7.0 ± 0.2 |
| Bilirubin | mg/dl | below 0.1 | below 0.1 | below 0.1 | below 0.1 | below 0.1 |
| ALP | IU/l | 133.5 ± 16.4 | 112.7 ± 21.0 | 127.1 ± 34.9 | 109.9 ± 17.5* | 134.6 ± 45.2 |
| AST | IUl | 81.5 ± 14.0 | 80.9 ± 14.8 | 81.8 ± 16.6 | 90.9 ± 18.0 | 75.6 ± 8.5 |
| ALT | IU/l | 44.5 ± 12.1 | 41.8 ± 7.6 | 41.5 ± 10.9 | 44.4 ± 12.4 | 43.2 ± 8.5 |
| GGT | g/dl | below 2 | below 2 | below 2 | below 2 | below 2 |
| CK | IU/l | 157.9 ± 102.3 | 165.0 ± 102.8 | 137.4 ± 59.5 | 301.9 ± 234.9 | 161.9 ± 111.9 |
| LDH | IU/l | 528.3 ± 426.1 | 576.8 ± 491.0 | 424.5 ± 233.2 | 728.6 ± 369.9 | 329.5 ± 113.9 |
| Na | nmol/l | 139.6 ± 2.9 | 139.6 ± 5.4 | 140.8 ± 3.2 | 137.3 ± 4.3 | 140.6 ± 3.2 |
| K | nmol/l | 22.6 ± 4.1 | 23.5 ± 7.3 | 21.5 ± 5.2 | 24.9 ± 4.2 | 20.2 ± 4.3 |
| Cl | nmol/l | 97.4 ± 2.4 | 98.1 ± 2.1 | 97.9 ± 0.9 | 96.5 ± 3.3 | 97.5 ± 1.7* |
| Creatine | mg/dl | 0.7 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.0 | 0.8 ± 0.1 |
| BUN | mg/dl | 19.4 ± 2.1 | 19.9 ± 3.1 | 19.6 ± 3.5 | 21.3 ± 2.8 | 21.1 ± 3.6 |
| Uric acid | mg/dl | 8.7 ± 1.6 | 6.9 ± 1.8 | 7.5 ± 1.2 | 6.8 ± 1.0* | 7.59 ± 1.61 |
| T.Chol | mg/dl | 84.2 ± 11.2 | 94.2 ± 17.7 | 88.5 ± 11.3 | 87.2 ± 10.0 | 89.7 ± 15.5 |
| H.Chol | mg/dl | 12.0 ± 2.2 | 15.5 ± 3.9* | 15.7 ± 2.5* | 16.0 ± 2.2* | 16.1 ± 3.3* |
| L.Chol | mg/dl | 15.9 ± 2.3 | 15.9 ± 3.6 | 16.0 ± 2.8 | 14.9 ± 2.6 | 14.7 ± 3.8 |
| TG | mg/dl | 82.7 ± 18.9 | 65.7 ± 9.8* | 68.8 ± 13.1 | 60.3 ± 11.1* | 64.7 ± 21.5 |
| Glucose | mg/dl | 403.0 ± 69.6 | 289.4 ± 112.1* | 338.7 ± 115.4 | 293.5 ± 81.0* | 392.3 ± 100.6 |
| Ca | nmol/l | 13.0 ± 0.3 | 12.6 ± 0.6 | 12.8 ± 0.5 | 12.2 ± 0.5* | 12.5 ± 0.4* |
| IP | mg/dl | 18.9 ± 3.3 | 19.5 ± 3.9 | 16.5 ± 4.2 | 17.9 ± 2.1 | 14.9 ± 2.6* |
Abbreviations: ALP: alkaline phosphatase, AST (GOT), glutamate oxaloacetate transaminase, ALT (GPT), glutamate pyruvate transaminase, GGT, γ-glutamyl transferase, CK: creatinine phosphokinase, LDH, lactate dehydrogenase, Na, Sodium, K, potassium, Cl, chloride, BUN, blood urea nitrogen, T. Chol: total cholesterol, H. Chol: HDL cholesterol, L. Chol: LDL cholesterol, TG, triglyceride, Ca, calcium, IP, inorganic phosphorus.
aCON: PBS (vehicle) treated with murine normal diet.
Each value represents mean ± S.D. Statistically significant from control (*P<0.05).