Fig. 2. Expressions of the genes in the MAPK signaling pathways in wildtype and sod-3(gk235) mutant. C. elegans was exposed to 1mg/l of AgNPs for 0, 4, 12, 24 and 48 h, with qRT-PCR performed for the analysis of gene expressions. The results are expressed in relative units compared to the beginning of the experiment (0 h = 1). Statistically significant differences were analyzed between the response of the wildtype and mutants using a one-way ANOVA (number = 3; mean ± standard error of mean, ^*p < 0.05, ^**p < 0.01, ^***p < 0.001).