Table 3.
BALF cytology of rats exposed to TiO2 nanoparticles
Cell type | Day 1 post-exposure | Day 7 post-exposure | Day 15 post-exposure | |||
---|---|---|---|---|---|---|
Control | Treated | Control | Treated | Control | Treated | |
Total cell | 5.246 | 5.361 | 4.166 | 4.230 | 4.650 | 4.780 |
Macrophage | 5.230 | 5.356 | 4.153 | 4.221 | 4.640 | 4.716 |
Neutrophil | 0.003 | 0.004 | 0.008 | 0.005 | 0.004 | 0.008 |
Lymphocyte | 0.013 | 0.002 | 0.005 | 0.004 | 0.006 | 0.057 |
Note: Rats were treated with 0 (control) or 11.39 mg/m3 (Treatment) TiO2 nanoparticles by inhalation for 2 weeks. Lung lavage was performed on 1,7, and 15 days post-exposure.
Mean values {(Cell counts/ml BALF) × 105} of the indicated animal groups are shown.