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. 2013 Mar;29(1):61–67. doi: 10.5487/TR.2013.29.1.061

Table 2.

Effect of crude extract of Houttuynia cordata Thunb. on serum MDA, creatinine and BUN levels in gentamicin-sulfate treated rats

Groups Parameters Serum malondialdehyde (nmol/dl) Serum creatinine (mg/dl) Blood urea nitrogen (mg/dl)

Control 0.063 ± 0.02 0.67 ± 0.04 17.55 ± 1.52
Houttuynia cordata Thunb (1000 mg/kg/day)b 0.060 ± 0.04# 0.77 ± 0.06# 19.21 ± 1.48#
Gentamicin sulfate (100 mg/kg/day)a 0.104 ± 0.03* 1.99 ± 0.35* 46.74 ± 2.81*
Gentamicin sulfate (100 mg/kg/day)a + HC (500 mg/kg/day)b 0.065 ± 0.06# 0.85 ± 0.18# 31.57 ± 2.74*#
Gentamicin sulfate (100 mg/kg/day)a + HC (1000 mg/kg/day) 0.051 ± 0.035*# 0.80 ± 0.08# 21.88 ± 1.70#

*p< .05 as compared with control group.

#p< .05 as compared with gentamicin group.

aIntraperitoneal injection.

bOral administration.