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. 2013 Apr 12;30(2):96–102. doi: 10.5114/pdia.2013.34158

Table 3.

Selected HLA frequency in patients with recurrent aphthous stomatitis (RAS), Behçet's disease (BD) and generally healthy (C)

Number of patients (n) HLA Allele frequency [%] Significance level (p) Authors
Study group Control group
RAS (31)
C (961)
Brazil		 A33
B35
B81		 19.4*
48.4*
6.5* 		6.5*
21.2*
0.8* 		0.016*
< 0.001*
0.036* 		Wilhelmsen et al.,2009 [48]
RAS (101)
C (97)
Turkey		 B51
45.5
46.3
0.905
 Özdemir et al., 2009 [49]
BD (100)
C (97)
Turkey
63.0*
46.3*
0.019*
BD (32)
C (310)
China
DRw8
37.5*
9.7*
< 0.0001*
Sun et al.,2001 [18]
RAS (20)
Finland		 B12 25.0 － － Malmström et al.,1983 [51]
RAS (20)
C (100)
UK
45.0*
22.0*
< 0.05*
 Lehner et al., 1982 [52]
BD (60)
C (100)
UK
46.6*
22.0*
< 0.01*
RAS (17)
C (70)
UK		 DR7
11.8
17.1
NS
BD (51)
C (70)
UK
39.2*
17.1*
< 0.01*
RAS (26)
C (84)
Italy		 DR7

B5		 61.5*

0* 		21.4*

27.3* 		< 0.0025*

< 0.04* 		Gallina et al., 1985 [53]
*

Statistically significant differences