Table 1.

Treatment of acne

	Comedonal acne	Papulopustular acne mild	Papulopustular acne medium	Nodular acne	Nodular/cystic acne
First-linetherapy	Local retinoid	Local retinoid, antibacterial drug	Oral antibiotic + local retinoid + benzyl peroxide	Oral antibiotic + local retinoid + benzyl peroxide	Oral isotretinoin
Alternativetherapy	Local retinoid, azelaic acid, salicylic acid	Local retinoid, antibacterial drug + alt. local retinoid or salicylic acid	Alt. oral antibiotic + alt. local retinoid + benzyl peroxide	Oral isotretinoin or alt. oral antibiotic + alt. local retinoid + benzyl peroxide + azelaic acid	High dose of oral antibiotic + local retinoid + benzyl peroxide
Alternative therapy for women	See first-line therapy	See first-line therapy	Oral antiandrogens + local retinoid, azelaic acid, local antibacterial drug	Oral antiandrogens + local retinoid ± oral antibiotic ± alt. antibacterial	High dose of antiandrogens + local retinoid + local antibacterial drug
Supportive therapy	Local retinoid	Local retinoid	Local retinoid + benzyl peroxide	Local retinoid + benzyl peroxide	Local retinoid + benzyl peroxide