Skip to main content
. 2013 Aug 27;170(2):317–327. doi: 10.1111/bph.12275

Figure 1.

Figure 1

ODQ inhibition of NO-stimulated NO-GC. (A) DEA-NO-induced cGMP production in HEK-GC cell homogenate in the presence of different concentrations of the NO-GC inhibitor ODQ (1, 10, 100 μM; 10 min pre-incubation); GSNO-induced cGMP production in HEK-GC cell homogenate in the presence of different concentrations of the NO-GC inhibitor ODQ (1, 10, 100 μM) (*P < 0.05, **P < 0.01 compared to non-stimulated control). (B) DEA-NO-induced cGMP production in murine platelets in the presence of ODQ (10 μM; 10 min pre-incubation). Data shown are mean ± SEM of n = 10 (***P = 0.0003, **P = 0.0019); GSNO-induced cGMP production in murine platelets in the presence of ODQ (10 μM; 10 min pre-incubation). Data shown are mean ± SEM of n = 8 (***P = 0.0003).