DEA-NO-induced relaxation of aortic rings. (A) Original traces of relaxation with DEA-NO from pre-contracted (1 μM PE) aortic rings of GCKO and WT in the absence and presence of ODQ (1, 10, 100 μM). ODQ had no effect on GCKO aorta. (B) Statistical analysis of DEA-NO-induced relaxation in aorta from GCKO and WT in the absence and presence of ODQ (1, 10, 100 μM) [*P < 0.05, compared to GCKO (DEA-NO 10 μM)]. (C) Original trace of relaxation with GSNO from pre-contracted (1 μM; PE) aortic rings of GCKO and WT in the absence and presence of ODQ (10 μM). (D) Statistical analysis of GSNO-induced relaxation in aorta from GCKO and WT in the absence and presence of ODQ (10 μM) [**P < 0.01, compared to GCKO (GSNO 100 μM)]. Data shown are mean ± SEM of n = 5 WT and n = 3 GCKO.