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Effects of 11R-VIVIT on mesangial expansion. (A) Representative photomicrographs of periodic acid–Schiff staining of glomeruli of BKS + PBS, db/db + PBS, db/db+11R-VIVIT mice at 20 weeks. (B) Semiquantitative analyses of mesangial expansion at 20 weeks (n = 5). Original magnification ×400. Data are mean ± SEM. *P < 0.01 versus BKS + PBS; #P < 0.01 versus db/db + PBS.
