Table 1.

Influences of 11R-VIVIT on physiological parameters in db/db and BKS mice

	BKS + PBS	db/db + PBS	db/db + 11R-VIVIT
Fasting glucose(mmol·L−1)	7.0 ± 0.2	30.8 ± 0.9*	29.8 ± 1.1*
Food intake (mL)	4.2 ± 0.1	9.8 ± 0.8*	9.2 ± 0.1*
Water intake (mL)	4.3 ± 0.1	14.4 ± 0.6*	13.3 ± 0.4*
Body weight (g)	25.1 ± 0.4	50.5 ± 1.6*	49.3 ± 1.1*
Kidney weight (g)	0.30 ± 0.01	0.44 ± 0.01*	0.33 ± 0.02△
Liver weight (g)	1.13 ± 0.05	2.83 ± 0.26*	2.82 ± 0.18*
Heart weight (g)	0.13 ± 0.01	0.13 ± 0.01	0.13 ± 0.01
Kidney/body weight (mg·g−1)	12.12 ± 0.28	8.69 ± 0.44*	7.00 ± 0.37*△

Data shown are mean ± SEM, n = 5. *P < 0.0.01 versus BKS + PBS; ^△P < 0.05 versus db/db + PBS.