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. 2013 Aug 23;41(21):9934–9944. doi: 10.1093/nar/gkt759

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — Two models of possible mechanisms for DdrB-mediated ssDNA annealing. (A) Two strands of ssDNA thread through different pores on a single DdrB pentamer. One strand is shown interacting with an extended face spanning multiple monomers within the pentamer. Annealing of strands is proposed to be facilitated by the forced juxtaposition of strands at a distinct location on the pentamer. (B) A strand of ssDNA is bound to the ‘top’ face of the DdrB pentamer with bases projecting outwards. A second strand, similarly bound to DdrB, senses for complementarity with the outwardly pointed bases.