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. 2013 Sep 20;41(21):e200. doi: 10.1093/nar/gkt845

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — PPV comparison on the mouse dataset. Heatmap depicting the pairwise dissimilarity (1-Pearson correlation) between the top 50 docetaxel resistance markers detected by DIDS using the scoring function on the mouse dataset. DIDS ranked the gene ABCB1B (indicated by the black box) at position 30. ABCB1B has been confirmed to confer resistance to docetaxel in a subgroup of the resistant mouse tumors in a separate study. It is also clear from this dissimilarity matrix that within these top 50 candidates, 29 genes (36 probes) show very high similarity as represented by the prominent red block.

Inline graphic — PPV comparison on the mouse dataset. Heatmap depicting the pairwise dissimilarity (1-Pearson correlation) between the top 50 docetaxel resistance markers detected by DIDS using the scoring function on the mouse dataset. DIDS ranked the gene ABCB1B (indicated by the black box) at position 30. ABCB1B has been confirmed to confer resistance to docetaxel in a subgroup of the resistant mouse tumors in a separate study. It is also clear from this dissimilarity matrix that within these top 50 candidates, 29 genes (36 probes) show very high similarity as represented by the prominent red block.