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. Author manuscript; available in PMC: 2013 Nov 20.
Published in final edited form as: Cell Rep. 2013 Oct 10;5(2):10.1016/j.celrep.2013.08.050. doi: 10.1016/j.celrep.2013.08.050

Figure 1. A 3′UTR reporter screen identifies candidate TET2-targeting miRNAs.

Figure 1

(A) A schematic of the high-throughput screen, in which ~460 human miRNA expression constructs were assayed one by one with human or mouse TET2 3′UTR reporters. (B) Data for a subset of candidate TET2-targeting miRNAs identified through the screen, as well as the non-targeting miR-128b, are shown. Normalized luciferase activities are plotted with the red line and with 1 representing averaged luciferase activities of controls. miRNAs that belong to the same family are boxed. Error bars represent standard deviation. N=4. See also Figure S1, S2 and Tables S1 and S6.