Table 3.
Growth kinetics in cultures co-expressing the mazF6 toxin with cognate and non-cognate antitoxins
| MazE | % Reduction in growth | |
|---|---|---|
| MazF6 expressed with non-cognate antitoxins |
1 |
17 |
| 2 |
30 |
|
| 3 |
11 |
|
| 4 |
17 |
|
| 5 |
19 |
|
| 7 |
33 |
|
| 9 |
24 |
|
| MazF6 alone |
- |
46 |
| MazE6 alone |
- |
5 |
| MazF6 | 6 | 4 |
Growth reduction associated with overexpression of the mazF6 toxin can be rescued by co-expression of its cognate antitoxin. Full rescue of the growth defect is not observed when co-expressed with non-cognate antitoxins.