Table 3.
Nebulization Efficiency (NE%) and RFP retained into vesicles in the nebulized fraction (NER) of liposomes containing 30 or 60 mg/mL of PC.
| NE% | FPD (µg) | FPF (%) | NER% | ||
|---|---|---|---|---|---|
| PC30 | Stage 1 | 35 ± 2.3 | 908 ± 23 | 9 ± 0.7 | 25 ± 0.7 |
| Stage 2 | 5 ± 0.5 | ||||
| Stage 3 | 4 ± 0.1 | ||||
| PC30 Chol | Stage 1 | 48 ± 3.9 | 736 ± 12 | 7 ± 1.3 | 25 ± 1.0 |
| Stage 2 | 5 ± 0.8 | ||||
| Stage 3 | 3 ± 0.2 | ||||
| PC30 Chol OA | Stage 1 | 51 ± 2.9 | 108 ± 32 | 11 ± 0.8 | 49 ± 3.3 |
| Stage 2 | 7 ± 0.2 | ||||
| Stage 3 | 4 ± 0.1 | ||||
| PC60 | Stage 1 | 41 ± 6.8 | 1300 ± 37 | 13 ± 0.9 | 45 ± 3.1 |
| Stage 2 | 10 ± 0.6 | ||||
| Stage 3 | 3 ± 0.1 | ||||
| PC60 Chol | Stage 1 | 54 ± 3.7 | 1260 ± 29 | 13 ± 1.2 | 49 ± 7.9 |
| Stage 2 | 9 ± 0.2 | ||||
| Stage 3 | 3 ± 0.1 | ||||
| PC60 Chol OA | Stage 1 | 64 ± 2.3 | 1685 ± 35 | 17 ± 1.7 | 55 ± 1.4 |
| Stage 2 | 12 ± 0.7 | ||||
| Stage 3 | 5 ± 0.1 |