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. 2013 May 10;5(2):277–293. doi: 10.3390/pharmaceutics5020277

Table 1.

Mesalazine solubility (mg/mL) in different solvents at varying pH and temperature.

Solvent pH Temperature (°C) Solubility (mg/mL)
70% ( v/v) ethanol 6.5 25 0.81
70% ( v/v) ethanol 6.5 37 1.40
70% ( v/v) ethanol 4.5 25 0.81
0.01 M HCl 2 25 0.89
0.1 M HCl 1 25 1.50
Distilled water 6.5 25 0.80