Table 3.

The molecular structure, pKa, LogP, aqueous solubility, and solubility in ethanol of prednisolone, hydrocortisone and mesalazine.

	Prednisolone	Hydrocortisone	Mesalazine
Molecular structure
pKa	-	-	2.15, 7.10, 12.30 [20]
Log P	1.62 [28]	1.61 [28]	0.64 [18]
Aqueous solubility at 25 °C	0.273 mg/mL [19]	0.311 mg/mL [19]	1.85 mg/mL [18]
Solubility in absolute ethanol	24.3 mg/mL at 25 °C [19]	14.7 mg/mL at 25 °C [19]	0.324 mg/mL at 24 °C [29]