Table 3.
Amino acid |
Serum concentration [μg/mL] |
Fold difference |
P-value
|
Trend |
||
---|---|---|---|---|---|---|
BrCA [n = 38] | HD [n = 10] | |||||
Aspartic acid |
Asp |
22.51 ± 8.4 |
21.16 ± 7.9 |
1.06 |
|
|
Glutamic acid |
Glu |
188.19 ± 101.8 |
96.71 ± 35.6 |
1.95 |
0.037 |
Higher in BrCA |
Asparagine |
Asn |
69.50 ± 25.3 |
67.43 ± 15.6 |
1.03 |
|
|
Serine |
Ser |
220.99 ±73.4 |
225.64 ± 43.7 |
0.98 |
|
|
Glutamine |
Gln |
632.40 ± 146.7 |
703.62 ± 126.3 |
0.90 |
|
|
Citrulline |
Cit |
55.67 ± 19.1 |
43.22 ± 8.4 |
1.29 |
|
|
Arginine |
Arg |
210.54 ± 57.8 |
180.39 ± 38.5 |
1.17 |
|
|
Alanine |
Ala |
795.24 ± 257.6 |
648.57 ± 205.4 |
1.23 |
|
|
Tyrosine |
Tyr |
123.16 ± 44.5 |
96.26 ± 25.0 |
1.28 |
|
|
Valine |
Val |
411.64 ± 123.4 |
320.08 ± 35.8 |
1.29 |
0.037 |
Higher in BrCA |
Phenylalanine |
Phe |
117.79 ± 31.5 |
106.87 ± 22.4 |
1.10 |
|
|
Isoleucine |
Ile |
118.02 ± 48.3 |
85.11 ± 17.5 |
1.39 |
|
|
Leucine |
Leu |
218.70 ± 81.0 |
170.95 ± 35.1 |
1.28 |
|
|
Ornithine |
Orn |
157.55 ± 44.6 |
160.92 ± 39.8 |
0.98 |
|
|
Lysine | Lys | 451.55 ± 146.7 | 478.04 ± 101.1 | 0.94 |
Serum concentrations are shown as means and standard deviations. All p-values are adjusted for both age and BMI by linear regression. A P-value <0.05 was considered significant.