Table 2.
Association Between Early AF Patterns and Death, Heart Failure, and Stroke Among Individuals With Incident AF
| AF Without 2‐Year Recurrence | Recurrent AF | Sustained AF | |||
|---|---|---|---|---|---|
| Total number with specific pattern | 63 | 162 | 207 | ||
| Primary outcome | |||||
| Death | |||||
| No. of events/person‐years | 29/431 | 87/678 | 141/852 | ||
| Adjustment | HR (95% CI) | P | HR (95%) CI | P | |
| Age and sex | Referent | 1.91 (1.25 to 2.90) | 0.003 | 1.99 (1.33 to 2.97) | <0.001 |
| Multivariable* | Referent | 2.04 (1.27 to 3.29) | 0.003 | 2.36 (1.49 to 3.75) | <0.001 |
| Secondary outcomes | |||||
| Heart failure | |||||
| No. of events/person‐years | 12/360 | 29/401 | 29/595 | ||
| Adjustment | HR (95% CI) | P | HR (95% CI) | P | |
| Age and sex | Referent | 2.08 (1.06 to 4.07) | 0.03 | 1.08 (0.54 to 2.13) | 0.84 |
| Multivariable* | Referent | 2.53 (1.19 to 5.38) | 0.02 | 1.23 (0.56 to 2.67) | 0.61 |
| Stroke | |||||
| No. of events/person‐years | 9/352 | 24/570 | 22/621 | ||
| Adjustment | HR (95% CI) | P | HR (95% CI) | P | |
| Age and sex | Referent | 1.52 (0.70 to 3.27) | 0.29 | 1.15 (0.53 to 2.50) | 0.73 |
| Multivariable* | Referent | 1.84 (0.77 to 4.38) | 0.17 | 1.32 (0.55 to 3.18) | 0.54 |
All models were adjusted for participants with indeterminate patterns as well as those with inadequate data for classification. AF indicates atrial fibrillation; HR, hazard ratio; CI, confidence interval.
Adjusted for age, sex, smoking status, systolic blood pressure, diabetes mellitus, history of heart failure, history of myocardial infarction, clinically significant murmur, and electrocardiographic left ventricular hypertrophy.
Adjusted for age, sex, systolic blood pressure, heart rate, electrocardiographic left ventricular hypertrophy, clinically significant murmur, body mass index, diabetes mellitus, and history of coronary heart disease.