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. 2013 Oct 25;2(5):e000136. doi: 10.1161/JAHA.113.000136

Table 7.

Stroke Prevention in Atrial Fibrillation Trial Populations

Trial Characteristics Dabigatran (RE‐LY)23 Rivaroxaban (ROCKET AF)24 Apixaban (ARISTOTLE)25
Participants, n 18 113 14 264 18 201
Median age 71 (mean) 73 70
Mean CHADS2 2.1 3.5 2.1
Mean TTR 64% 55% 62%
Median CrCl 68 67 N/A*

CrCl indicates creatinine clearance; CHADS2, congestive heart failure, hypertension, age, diabetes, stroke; TTR, time in therapeutic range.

*

Data on renal function presented as 83% with CrCl ≥50 mL/min.