Table 2.
Characteristics According to Quintiles of the 3 FlOP Measurements in Controls From the Nurses' Health Study*
| Characteristic | FlOP_360 | FlOP_320 | FlOP_400 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Q1 | Q3 | Q5 | Q1 | Q3 | Q5 | Q1 | Q3 | Q5 | |
| Age, y | 59.0 (7.5) | 59.1 (6.7) | 60.5 (6.5) | 58.9 (6.9) | 60.2 (6.3) | 60.4 (6.2) | 58.5 (6.7) | 59.5 (6.3) | 60.7 (6.5) |
| BMI, kg/m2 | 25.8 (4.5) | 25.4 (4.6) | 24.7 (3.9) | 25.1 (3.9) | 25.3 (4.5) | 24.7 (3.9) | 26.2 (4.7) | 25.0 (4.2) | 25.0 (4.1) |
| Current smoker, % | 3 | 22 | 33 | 4 | 28 | 24 | 3 | 19 | 58 |
| Alcohol intake, g/day | 3.3 (6.8) | 5.3 (8.1) | 6.5 (10.5) | 5.6 (11.2) | 6.7 (10.6) | 5.3 (10.1) | 3.9 (7.6) | 6.0 (9.6) | 7.2 (11.4) |
| Diabetes,* % | 6 | 7 | 4 | 5 | 9 | 5 | 7 | 6 | 4 |
| High cholesterol,* % | 35 | 46 | 47 | 32 | 45 | 41 | 43 | 39 | 48 |
| Hypertension,* % | 24 | 27 | 38 | 17 | 35 | 35 | 27 | 22 | 44 |
| CVD biomarkers | |||||||||
| Total cholesterol, mmol/L | 5.3 (1.3) | 6.0 (1.1) | 5.9 (1.2) | 5.6 (1.1) | 5.9 (1.1) | 5.8 (1.0) | 5.6 (0.9) | 5.8 (1.0) | 5.9 (1.4) |
| LDL‐C, mmol/L | 3.1 (1.0) | 3.6 (1.1) | 3.6 (1.1) | 3.3 (0.9) | 3.5 (1.0) | 3.4 (0.9) | 3.3 (0.8) | 3.4 (0.9) | 3.5 (1.2) |
| HDL‐C, mmol/L | 1.4 (0.4) | 1.5 (0.5) | 1.6 (0.5) | 1.5 (0.4) | 1.5 (0.4) | 1.6 (0.4) | 1.5 (0.4) | 1.6 (0.5) | 1.6 (0.5) |
| Triglycerides, mmol/L | 1.3 (0.6) | 1.4 (0.7) | 1.3 (0.8) | 1.2 (0.5) | 1.4 (0.8) | 1.3 (0.8) | 1.4 (0.6) | 1.4 (0.9) | 1.3 (0.7) |
| CRP, g/L | 0.3 (0.4) | 0.3 (0.4) | 0.4 (0.5) | 0.3 (0.5) | 0.3 (0.3) | 0.4 (0.5) | 0.4 (0.5) | 0.4 (0.6) | 0.4 (0.4) |
Quintiles 1 (Q1), 3 (Q3), and 5 (Q5) among the controls. BMI indicates body mass index; CRP, C‐reactive protein; CVD, cardiovascular disease; FlOP, fluorescent oxidation product; HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein cholesterol.
*
Values are means (SDs) or percentages and are standardized to the distribution of smoking status.
*
Self‐reported diagnosis before blood draw.