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. 2013 Oct 25;2(5):e000299. doi: 10.1161/JAHA.113.000299

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© 2013 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an Open Access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 2. — Celiac ganglionectomy blocked the effect of leptin on endothelial function and blood pressure response. A, Vasoconstriction responses of mesenteric arterioles to NE. B, Vasorelaxation responses of mesentery arterioles to SNP. C, Vasorelaxation responses of mesentery arterioles to Ach. D, Response of systolic blood pressure to angiotensin II. *P<0.05, **P<0.01, ***P<0.001 for comparisons between mice receiving celiac ganglionectomy or sham operation with subsequent leptin treatment. Ach indicates acetylcholine; Ang II, angiotensin II; Gx, ganglionectomy; NE, norepinephrine; PBS, phosphate‐buffered saline; SNP, sodium nitroprusside; WT, wild type.