Table 1.
Patient Characteristics by Doppler Results
| No Proximal or Distal Disease (n=5313) | Postexercise Proximal Disease and No Distal Disease (n=1298) | Resting Proximal Disease and No Distal Disease (n=2287) | Distal Disease and No Proximal Disease (n=1729) | Postexercise Proximal and Distal Disease (n=515) | Resting Proximal and Distal Disease (n=1589) | |
|---|---|---|---|---|---|---|
| Age, y | 64.5±13.7 | 65.0±11.8 | 68.4±11.3 | 73.0±11.0 | 70.6±9.9 | 71.1±10.9 |
| Men | 2876 (54.1%) | 786 (60.6%) | 1309 (57.2%) | 1085 (62.8%) | 333 (64.7%) | 915 (57.6%) |
| Decedents | 714 (13.4%) | 213 (16.4%) | 714 (31.2%) | 579 (33.5%) | 118 (22.9%) | 701 (44.1%) |
| Years of follow‐up | 5.8±2.8 | 6.4±3.0 | 5.9±3.2 | 5.6±3.1 | 6.5±3.0 | 5.8±3.4 |
| Obesity | 2214 (41.7%) | 519 (40.0%) | 760 (33.2%) | 626 (36.2%) | 157 (30.5%) | 522 (32.9%) |
| Systolic BP, mm Hg | 134.9±20.3 | 138.6±20.5 | 144.7±24.0 | 141.8±22.3 | 140.3±20.8 | 146.4±24.4 |
| Missing | 175 | 37 | 99 | 110 | 18 | 77 |
| Diastolic BP, mm Hg | 76.0±10.5 | 74.6±10.6 | 74.0±11.4 | 73.6±10.6 | 73.7±10.6 | 74.3±11.4 |
| Missing | 341 | 56 | 182 | 201 | 21 | 144 |
| Ever smoked | 4032 (75.9%) | 1147 (88.4%) | 2128 (93.0%) | 1340 (77.5%) | 462 (89.7%) | 1400 (88.1%) |
| Diabetes | 1033 (19.4%) | 328 (25.3%) | 575 (25.1%) | 633 (36.6%) | 134 (26.0%) | 493 (31.0%) |
| Hypertension | 2994 (56.4%) | 928 (71.5%) | 1752 (76.6%) | 1257 (72.7%) | 385 (74.8%) | 1255 (79.0%) |
| Dyslipidemia | 3565 (67.1%) | 1074 (82.7%) | 1874 (81.9%) | 1246 (72.1%) | 409 (79.4%) | 1218 (76.7%) |
| CHD | 1996 (37.6%) | 655 (50.5%) | 1366 (59.7%) | 913 (52.8%) | 283 (55.0%) | 964 (60.7%) |
| Heart failure | 424 (8.0%) | 98 (7.6%) | 299 (13.1%) | 317 (18.3%) | 32 (6.2%) | 317 (19.9%) |
| CKD | 244 (4.6%) | 63 (4.9%) | 158 (6.9%) | 137 (7.9%) | 35 (6.8%) | 140 (8.8%) |
| CVD | 921 (17.3%) | 422 (32.5%) | 883 (38.6%) | 522 (30.2%) | 155 (30.1%) | 595 (37.4%) |
| COPD | 553 (10.4%) | 192 (14.8%) | 492 (21.5%) | 250 (14.5%) | 88 (17.1%) | 369 (23.2%) |
| Lipid‐lowering medication use | 1641 (30.9%) | 588 (45.3%) | 969 (42.4%) | 552 (31.9%) | 216 (41.9%) | 540 (34.0%) |
| Aspirin use | 1903 (35.8%) | 598 (46.1%) | 1031 (45.1%) | 717 (41.5%) | 238 (46.2%) | 640 (40.3%) |
| Resting ABI | 1.04±0.18 | 0.87±0.18 | 0.52±0.19 | 0.67±0.20 | 0.69±0.15 | 0.49±0.19 |
| Missing | 5 | 10 | 10 | 11 | 1 | 7 |
| CLI | 273 (5.1%) | 13 (1.0%) | 390 (17.1%) | 435 (25.2%) | 8 (1.6%) | 536 (33.7%) |
Shown are mean±standard deviation for continuous variables and frequency (%) for categorical variables and missing values. Proximal and distal disease for each subject is classified separately based on the most severe disease status (no disease < postexercise disease < resting disease) across both legs. Those with no proximal Doppler assessments were classified based on imputed disease status (similarly for those with no distal Doppler assessment). ABI indicates ankle brachial index; BP, blood pressure; CHD, coronary heart disease; CKD, chronic kidney disease; CLI, critical limb ischemia; COPD, chronic obstructive pulmonary disease; CVD, cerebrovascular disease.