Table 1.
Parameter | Sham | CHF | ||||||
---|---|---|---|---|---|---|---|---|
Average | Min | Med | Max | Average | Min | Med | Max | |
HR, min−1 | 268±13 | 203 | 259 | 336 | 240±8 | 201 | 247 | 266 |
ESP, mm Hg | 118.5±5 | 91 | 118.5 | 142 | 92±1* | 84 | 93.5 | 101 |
EDP, mm Hg | 8.3±1 | 5 | 7 | 14 | 24±1* | 20.6 | 23.2 | 29 |
ESV, mL | 132±18 | 62 | 114 | 218 | 240±65* | 154.0 | 234.4 | 346 |
EDV, mL | 262±31 | 130 | 273 | 388 | 307±57 | 247.0 | 284.8 | 397 |
SV, mL | 164±16 | 93 | 182 | 215 | 88±16* | 52 | 89 | 104 |
CO, mL/min | 43.5±5 | 19 | 50 | 59 | 20.9±1* | 14 | 22 | 24 |
Ea, mm Hg/μL | 0.8±0.1 | 0.5 | 1 | 0.6 | 1.1±0.1 | 0.8 | 1.1 | 2 |
EF, % | 59±3.4 | 48 | 54.5 | 77 | 28.4±7* | 18.9 | 27.41 | 40 |
dP/dTmax, mm Hg/s | 6823±350 | 5482 | 6729 | 8600 | 3962±200* | 3034 | 3937 | 4688 |
SW, mm Hg×mL | 16 167±1928 | 7872 | 18940 | 23 102 | 5124±457* | 3040 | 5704 | 6696 |
−dP/dTmin, mm Hg/s | 4664±268 | 5841 | 4684 | 3505 | 2515±162* | 3436 | 2249 | 1939 |
Tau (W), ms | 15.2±1.2 | 9 | 14.3 | 21 | 21.9±1* | 16 | 22 | 26 |
Tau (G), ms | 18.8±1.1 | 13 | 17.9 | 23 | 31.7±3.8* | 18 | 27.8 | 55 |
Data are presented as average±SE. n=9 per group. Min, med, and max, minimum, median, and maximum parameter values, respectively. CHF indicates congestive heart failure; CO, cardiac output; dP/dTmax, peak rate of pressure rise; −dP/dTmin, peak rate of pressure decline; Ea, arterial elastance; EDP, end‐diastolic pressure; EDV, end‐diastolic volume; EF, ejection fraction; ESP, end‐systolic pressure; ESV, end‐systolic volume; HR, heart rate; SV, stroke volume; SW, stroke work; Tau (G), relaxation time constant using the Gauss–Seidel method; Tau (W), relaxation time constant calculated by Weiss method (regression of log pressure).
P<0.05, CHF vs sham.
P<0.005, CHF vs sham.