Table 5. Correlation of quality control measures.
Correlations of quality control measures. Each quality control measure is organized by the 4 categories (clinical, tissue, RNA, microarray) and then correlated for cerebellum data. The significant correlations are in bold (p < 0.01). Abbreviations are the same as in Table 1.
| Clinical Quality | Tissue Quality | RNA Quality | Microarray Quality | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age | AFS | pH | PMI | Freezer time | 28S / 18S | 3′ / 5′ GAPDH | 3′ / 5′ ACTB | RIN | cRNA (∼nts) | PC | SF | ACI | Type 1/2 | |
| Age | 1.00 | |||||||||||||
| AFS | 0.19 | 1.00 | ||||||||||||
|
| ||||||||||||||
| pH | −0.20 | −0.44 * | 1.00 | |||||||||||
| PMI | −0.05 | −0.13 | 0.12 | 1.00 | ||||||||||
| Freezer time | −0.19 | 0.17 | 0.00 | −0.44 | 1.00 | |||||||||
| 28S/18S | −0.04 | −0.25 | 0.33 | 0.11 | −0.18 | 1.00 | ||||||||
| 3′/5′ GAPDH | 0.08 | 0.21 | −0.35 | 0.13 | −0.01 | −0.64 | 1.00 | |||||||
| 3′/5′ ACTB | −0.02 | −0.02 | −0.20 | 0.21 | −0.18 | −0.48 | 0.86 | 1.00 | ||||||
| RIN | −0.02 | −0.52 | 0.31 | 0.25 | −0.37 | 0.68 | −0.63 | −0.37 | 1.00 | |||||
| cRNA (∼nts) | −0.15 | −0.21 | 0.22 | −0.19 | 0.34 | 0.14 | −0.42 | −0.34 | 0.28 | 1.00 | ||||
|
| ||||||||||||||
| PC | −0.04 | −0.46 | 0.38 | 0.17 | −0.40 | 0.53 | −0.47 | −0.17 | 0.63 | 0.21 | 1.00 | |||
| SF | 0.01 | 0.52 | −0.25 | −0.34 | 0.45 | −0.41 | 0.27 | 0.02 | −0.70 | −0.22 | −0.82 | 1.00 | ||
| ACI | −0.06 | −0.53 | 0.46 | −0.03 | −0.10 | 0.58 | −0.70 | −0.49 | 0.63 | 0.39 | 0.65 | −0.41 | 1.00 | |
| Type 1 / 2 | 0.17 | 0.49 | −0.61 | 0.16 | 0.01 | −0.42 | 0.47 | 0.24 | −0.34 | −0.33 | −0.48 | 0.30 | −0.59 | 1.00 |
*
Bold correlations were significant (r > |0.267|, p < 0.01, df = 89).