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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Clin Perinatol. 2012 Dec;39(4):10.1016/j.clp.2012.09.006. doi: 10.1016/j.clp.2012.09.006

Table 4.

Unresolved issues

Maternal care
  • What is the best time to clamp the cord in relation to administration of uterotonic drugs in active management of the second stage of labor?

  • How best to optimize cord clamping time in cases of maternal hemorrhage?

  • Should the cord-clamping time be different in women positive for HIV?

Resuscitation
  • How to consistently maintain the infant’s position in relation to placenta, especially in cesarean deliveries?

  • Can we carryout resuscitation with the umbilical cord still attached to the undelivered placenta?

  • How to record the timing of birth, and timing of various steps of neonatal resuscitation, including the recording of the Apgar scores?

Cord Clamping
  • How long a delay is ideal? 30 seconds? 60 seconds? Or other durations depending upon the infant condition?

  • What should be the location of baby while clamping the cord in relation to the placenta in cesarean sections?

  • Should one document the exact time of cord clamping in all births?

  • Up to what lower gestational age, benefits from delayed cord clamping can be demonstrated?

Clamping versus Milking of the cord?
  • Are there differential benefits between milking and delayed clamping?

  • What is the appropriate length of the cord to be milked?

  • How “fast” and how many times milking is appropriate?

At Risk Infants
  • What should be the standard for cord clamping in births at high altitudes?

  • What should be done in infants with a risk for fetal polycythemia (e.g., severe intra uterine growth restriction, infant of diabetic mothers, large and small for gestational age)

Guidelines and education
  • Need for developing standardized protocols

  • Continued monitoring of outcomes for collective learning

  • Periodic reassessment of guidelines