Table 2.
Hematological and biochemical markers during treatment with oral solution of deferiprone (Ferriprox 100 mg/mL) in nine children (4 under 6 years, 5 above 6 years) with transfusion dependent hemoglobinopathies.
| Parameters | Total | <6 years | >6 years | |||
|---|---|---|---|---|---|---|
| Initial | Final | Initial | Final | Initial | Final | |
| White blood cells (×109/L) | 6.5 ± 0.6 | 6.7 ± 1.2 | 5.9 ± 1.4 | 6.3 ± 2.1 | 6.8 ± 1.3 | 6.1 ± 0.8 |
| Hemoglobin (g/L) | 95 ± 8 | 94 ± 6 | 89 ± 9 | 93 ± 7 | 97 ± 1.1 | 93 ± 7 |
| Platelets (×109/L) | 178.2 ± 56.9 | 165.4 ± 58.4 | 182.4 ± 91.8 | 175.5 ± 56.2 | 174.8 ± 66.3 | 180.7 ± 95.7 |
| AST (U/L) | 43.5 ± 15.4 | 39.2 ± 14.6 | 42.3 ± 17.5 | 39.7 ± 20.5 | 38.9 ± 13.8 | 41.8 ± 13.7 |
| ALT (U/L) | 53.1 ± 16.5 | 51.4 ± 13.7 | 50.8 ± 12.9 | 49.8 ± 19.1 | 54.2 ± 17.2 | 51.8 ± 15.4 |
| Creatinine (μmol/L) | 65 ± 12 | 72 ± 15 | 68 ± 12 | 70 ± 11 | 68 ± 19 | 72 ± 16 |
| Ferritin (μg/L) | 2440 ± 1275 | 1420 ± 730* | 2250 ± 880 | 1575 ± 810* | 2950 ± 1550 | 1390 ± 985* |
Values presented as mean ± SE; *P < 0.05.