Table 2.

Plasma amino acid levels.

Amino acid	Controls (n = 60)	CRPS (n = 160)	P
	(umoles/L)	(umoles/L)
L-Aspartate	7.47 ± 0.36	9.27 ± 0.30	0.00473
L-Glutamate	52.51 ± 4.29	77.22 ± 3.52	0.00057
L-Asparagine	51.91 ± 1.69	47.59 ± 0.93
L-Serine	107.75 ± 3.54	100.16 ± 2.23
L-Glutamine	572.73 ± 13.2	579.40 ± 9.74
D-Serine	1.94 ± 0.07	2.06 ± 0.05
L-Citrulline	28.17 ± 1.20	30.58 ± 0.84
L-Threonine	135.07 ± 5.04	133.34 ± 3.08
Glycine	302.99 ± 12.6	318.87 ± 9.31
L-Histidine	65.88 ± 2.28	68.07 ± 1.91
L-Arginine	67.49 ± 3.33	48.82 ± 1.59	0.000001
L-Alanine	426.06 ± 14.2	447.11 ± 11.1
Taurine	67.46 ± 2.61	72.87 ± 2.29
L-Tyrosine	80.72 ± 2.82	77.39 ± 1.77
L-Valine	260.67 ± 8.54	243.64 ± 5.46
L-Methionine	23.81 ± 0.87	20.76 ± 0.50
L-Isoleucine	74.93 ± 3.51	66.89 ± 1.90
L-Tryptophan	41.91 ± 1.25	36.96 ± 0.82	0.04210
L-Phenylalanine	48.23 ± 1.45	46.53 ± 0.92
L-Leucine	122.71 ± 4.70	108.53 ± 2.57
L-Ornithine	70.29 ± 3.53	94.38 ± 3.12	0.00002
L-Lysine	160.89 ± 5.76	155.57 ± 3.37
L-Kynurenine	1.79 ± 0.07	1.80 ± 0.06

This table lists the plasma amino acid levels in CRPS and healthy control subjects. All values are given in micromoles per liter ± the standard error of the mean. Significant difference in plasma amino acid levels between the control and CRPS groups was determined with the Student's t-test adjusted for multiple testing (Bonferroni). Bonferroni adjusted probability values (the P value from the Student's t-test multiplied by 23, the number of amino acids evaluated) less than 0.05 are highlighted in bold.