Table 1.

Etiologies for short stature and common screening tests

Etiology	Screening tests
Genetic short stature
Chromosomal aneuploidy, including Turner syndrome	Karyotype in girls
Microdeletion or duplication
Single gene disorders
Polygenic
Constitutional delay of growth and puberty
Hormonal pathologies
Growth hormone deficiency	IGF-1, IGF BP-3
Hypothyroidism	Thyroid function tests
Cushing syndrome
Systemic diseases
Inflammatory disease, e.g. IBD, JIA	erythrocyte sedimentation rate
Celiac disease	tissue transglutaminase antibodies
Renal disorders	electrolytes, creatinine
Liver disorders	liver function tests
Hematologic disorders	complete blood count
Birth history of IUGR/SGA
Medications