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. 2013 Nov 20;8(11):e80700. doi: 10.1371/journal.pone.0080700

Figure 6. CT genotype of the rs7120118 variation increases the mRNA levels of NR1H3 as compared to TT genotype.

Figure 6

(A) qPCR analysis indicates ∼50% increase in the mRNA levels of NR1H3 in the temporal cortex of AD patients with rs7120118 CT genotype as compared to TT genotype (*p<0.05, ANOVA LSD, n = 31/33/13, rs7120118 genotypes TT/CT/CC, respectively). (B–D) The mRNA levels of ABCA1, ABCG1 and APOE do not change with respect to the rs7120118 genotype (ABCA1 n = 31/35/15; ABCG1 n = 28/29/11; APOE n = 23/23/14, rs7120118 genotypes TT/CT/CC, respectively). Mean values are indicated in the graphs.