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. 2013 Nov 20;8(11):e82267. doi: 10.1371/journal.pone.0082267

Figure 4. Processing defects of enamel matrix proteins in the cKO mice.

Figure 4

(A) Darker and slightly higher amelogenin staining in P7 cKO mouse in the enamel matrix (white arrow) as compared to the control (black arrow), residual enamelin in P7 cKO enamel matrix (red arrow), and higher ameloblastin staining in P7 cKO enamel matrix (blue arrow). Higher magnifications are shown in insets. (B) qPCR showing a significant decrease in KLK4 mRNA expression and slight increase in MMP-20 mRNA expression at P7. No difference in amelogenin, enamelin, and ameloblastin mRNA expression at P7. Values of P < 0.05 were considered statistically significant (***P < 0.001 and *P < 0.05).