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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Br J Haematol. 2013 Sep 6;163(3):10.1111/bjh.12542. doi: 10.1111/bjh.12542

Figure 2. Incidence and magnitude of hyperuricaemia.

Figure 2

A. Mean ± standard error of the mean (SEM) uric acid (UA) levels at initial measurement in each treatment group. B. Mean ± SEM initial UA values and associated initial lactate dehydrogenase (LDH) values. LDH <2x upper limit of normal (ULN) vs. LDH ≥2x ULN, p = 0.005 (unpaired t test). C. Incidence of hyperuricaemia in each treatment group. D. Incidence of hyperuricaemia associated with initial LDH values. LDH <2x ULN vs. LDH ≥2x ULN, p = 0.02 (Fisher’s exact test). E. Time course of UA level decline for all 29 episodes of hyperuricaemia in 25 patients. Time 0 represents the time of peak UA. The dashed line represents a level of 475.8 μmol/l – the cut-off point for hyperuricaemia. F. Percentage of episodes of hyperuricaemia that resolve within 24, 48, or 72 h after rasburicase administration.