Table 5.
Baseline to 6-month effect sizes and mean (SD) changes in physical functioning scores across levels of DAS28 treatment response in the cross-validation sample (n = 276)
|
Total ES |
Non- or moderate responders |
Good responders |
F | RV | 95% CI | |
|---|---|---|---|---|---|---|
| (n = 142) | (n = 134) | |||||
| HAQ-ADI |
|
|
|
|
|
|
| Observed |
0.55 |
−0.20 (0.52) |
−0.62 (0.58) |
38.59 |
1.00 |
|
| Predicted |
0.37 |
−0.14 (0.54) |
−0.50 (0.55) |
30.12 |
0.78 |
0.35 to 1.69 |
| HAQ-SDI |
|
|
|
|
|
|
| Observed |
0.49 |
−0.17 (0.44) |
−0.49 (0.49) |
30.63 |
1.00 |
|
| Predicted |
0.38 |
−0.14 (0.53) |
−0.51 (0.55) |
32.38 |
1.06 |
0.44 to 2.25 |
| PF-10 |
|
|
|
|
|
|
| Observed |
0.40 |
5.53 (20.15) |
19.63 (20.74) |
32.80 |
1.00 |
|
| Predicted from HAQ-ADI |
0.55 |
7.85 (19.99) |
24.33 (21.98) |
42.52 |
1.18 |
0.63 to 3.35 |
| Predicted from HAQ-SDI | 0.48 | 6.23 (15.34) | 16.98 (16.68) | 31.09 | 0.86 | 0.43 to 2.36 |
PF-10 = SF-36 physical functioning scale; HAQ-SDI = Health Assessment Questionnaire standard disability index; HAQ-ADI = Health Assessment Questionnaire alternative disability index; ES = Cohen’s d effect size; F = F-statistic from one-way ANOVA; RV = Relative validity (ratio of F-statistics compared with observed score); 95% CI = 95% bootstrap bias-corrected and accelerated confidence interval.