Skip to main content
. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: J Pharm Biomed Anal. 2013 Aug 23;86:10.1016/j.jpba.2013.08.007. doi: 10.1016/j.jpba.2013.08.007

Table 3.

Matrix effect in PBMC extract (n=3).

Conc (ng/mL) 70% MeOH-tris
(mean±SD)		 PBMC extract
(mean±SD)		 ME,%
0.5 Peak area 0.403±0.006 0.498±0.011 123
Ratio 0.0220±0.0005 0.0255±0.0006 116
1.5 Peak area 1.08±0.04 1.24±0.05 115
ratio 0.0589±0.0005 0.0642±0.0016 109
40 peak area 28.7±1.5 28.1±0.7 98
ratio 1.62±0.05 1.39±0.05 86

Note: peak area is expressed as ×104 cps. Ratio is calculated with peak area of drug devided by peak area of IS.