Table 3.
Survival analysis for recurrent hepatitis C
| Multivariate Cox regression analysis assessing factors predictive of recurrent chronic hepatitis C at 2 years | ||||
|---|---|---|---|---|
| HCV recurrence – 2yrs | Hazard Ratio | 95% CI | P-value | |
| Recipient IL28B genotype | ||||
| Overall (additive genetic model) | 0.619 | 0.434 | 0.883 | 0.0081 |
| CC vs TT | 0.383 | 0.190 | 0.775 | 0.0076 |
| CT vs TT | 0.599 | 0.334 | 1.073 | 0.0850 |
| Pre-transplant MELD score | 1.050 | 1.017 | 1.085 | .0029 |
| Pre-transplant ALT level (IU/mL) | 1.004 | 1.001 | 1.007 | 0.0042 |
| Multivariate Cox regression analysis assessing factors predictive of recurrent chronic hepatitis C virus at 5 years | ||||
|---|---|---|---|---|
| HCV recurrence – 5yrs | Hazard Ratio | 95% CI | P-value | |
| Recipient IL28B genotype | ||||
| Overall (additive genetic model) | 0.632 | 0.466 | 0.856 | 0.0031 |
| CC vs TT | 0.392 | 0.216 | 0.711 | 0.0021 |
| CT vs TT | 0.561 | 0.333 | 0.946 | 0.0301 |
| Pre-transplant MELD score | 1.035 | 1.004 | 1.067 | 0.0260 |
| Pre-transplant ALT level (IU/mL) | 1.004 | 1.001 | 1.007 | 0.0041 |