Table 2.
|
Hemagglutination inhibition |
Microneutralization assays |
||
---|---|---|---|---|
Pre-vaccination | Post-vaccination | Pre-vaccination | Post-vaccination | |
N |
60 |
60 |
60 |
60 |
Seroprotection rate%a |
6.7 |
66.7d |
NA |
NA |
Seroconversion rate%b |
NA |
48.3 |
NA |
NA |
GMTc |
6.8 |
64.9d |
10.7 |
288.4d |
GMT Fold-change | NA | 9.5 | NA | 26.9 |
aSeroprotection rate = percentage of subjects with hemagglutinin inhibition titers ≥ 1:40.
bSeroconversion rate = percentage of subjects with pre-vaccination hemagglutinin inhibition titers ≤ 1:10 and post-vaccination titers ≥ 1:40.
cGMT = geometric mean titer.
dp ≤ 0.05 vs pre-vaccination.