Table 1.
Effect of aqueous extract of H. erinaceus on different gastric parameters of ethanol-induced rats.
| Animal groups | Treatment (5 mL/kg dose) | Ulcer area (mm2) Mean ± SEM |
Ulcer inhibition (%) | Mucus production (g) |
|---|---|---|---|---|
| 1 | Non-treatment group | 0 | 0 | 0.42 ± 0.06∗# |
| 2 | Ulcer control group | 894.00 ± 36.69# | 0 | 0.79 ± 0.03# |
| 3 | Omeprazole (20 mg/kg) | 285.90 ± 19.64* | 67.45 | 1.56 ± 0.07* |
| 4 | H. erinaceus (50 mg/kg) | 727.20 ± 26.88∗# | 18.14 | 0.79 ± 0.03# |
| 5 | H. erinaceus (100 mg/kg) | 602.40 ± 29.43∗# | 32.17 | 0.82 ± 0.04# |
| 6 | H. erinaceus (200 mg/kg) | 453.60 ± 27.89∗# | 48.60 | 0.93 ± 0.06# |
| 7 | H. erinaceus (400 mg/kg) | 240.00 ± 17.31* | 72.97 | 1.18 ± 0.04∗# |
All values were expressed as mean ± standard error of mean. *Significant difference (P < 0.05) when compared with the ulcer control (group 2). #Significant difference (P < 0.05) when compared with the omeprazole (group 3).