Figure 1. Efficient recovery from MMS reveals a strong synergistic functionality between Sgs1/Top3 and Rad9.
(A) Survival was monitored as described in Materials and Methods after 70 min exposure to different concentrations of MMS for the indicated strains: wild type (LBy-1), sgs1Δ (LBy-129), top3Δ (LBy-7), rad9Δ (LBy-316), sgs1Δ rad9Δ (LBy-44) and top3Δ rad9Δ (LBy-27). (B) Survival as in A for isogenic strains rad24Δ (LBy-391), sgs1Δ rad24Δ (LBy-36) and top3Δ rad24Δ (LBy-28). The wild type, sgs1Δ and top3Δ survival curves are added in for comparison from A.