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. 2013 Nov 20;8(11):e81068. doi: 10.1371/journal.pone.0081068

Figure 8. Energetic contribution to the differences in the binding free energies (ΔΔGBinding) between wild type HDM2 and alanine mutant variants for binding to the indicated ligands.

Figure 8

Residues contributing > 2 kcal/mol are highlighted in red, and are further depicted in Venn diagram below.