. Author manuscript; available in PMC: 2013 Nov 21.

Published in final edited form as: Medchemcomm. 2013;4(11):10.1039/C3MD00185G. doi: 10.1039/C3MD00185G

Table 2. IC₅₀ values at 24 hr for cell growth inhibition in different human normal cell lines.

	Origin/Cell line, IC₅₀, μM
Compound	Lung Fibroblast IMR-90 (CCL186)	Mammary Epithelial HMEpC	Pancreatic Epithelial HPDE (ACBRI 515)
NOSH-NAP	20.0 ± 2.5	13.8 ± 0.9	22.0 ± 1.8
NOSH-SUL	21.7 ± 1.7	15.2 ± 0.7	> 25

Normal human lung fibroblast, mammary epithelial, and pancreatic epithelial cells were treated with NOSH-naproxen (NOSH-NAP) and NOSH-sulindac (NOSH-SUL) as described under Experimental Section/Biology. Cell numbers were determined at 24 h from which IC₅₀ values were calculated. Results are mean ± S.E.M. of three different experiments done in duplicate.

Table 2. IC50 values at 24 hr for cell growth inhibition in different human normal cell lines.

Table 2. IC₅₀ values at 24 hr for cell growth inhibition in different human normal cell lines.